What effects do competition and specificity (affinity and kd) have on transduction?

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Answer 1

Efficacy is the capacity of a medication to elicit a reaction after binding to the receptor, whereas potency (given as ED50) is the drug range across which a response is produced. Simply put, a drug's potency is its concentration, and its efficacy is its capacity.

An explanation of antibody affinity and KD value.

More than 840 RabMAb antibodies from Abcam's line of Rabbit Monoclonal Antibodies have had their KD values thoroughly tested in order to determine not only their individual KD values but also the average affinity of a RabMAb antibody. Based on a comparison with data from the published literature for mouse monoclonal antibodies, RabMAb antibodies seem to have an affinity that is typically 1-2 orders of magnitude higher.

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Related Questions

As the island of hawaii continues to move away from the mantle plume, a new submarine volcano will be created. off which coast would you expect the new submarine volcano to be forming?

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As the island of Hawaii continues to move away from the mantle plume, a new submarine volcano will be created. off southeast coast you would expect the new submarine volcano to be forming

     The combined processes of magma creation, volcano eruption and growth, and ongoing Pacific Plate movement over the immobile Hawaiian "hot-spot" have produced a lengthy trail of volcanoes over the Pacific Ocean floor during the past 70 million years.

    The Island of Hawaii will be carried beyond the hotspot by plate motion as the Pacific Plate continues to move in a west-northwest direction, creating the conditions for the development of a new volcanic island in its stead. This procedure may already be in motion. A submerged volcano called Loihi Seamount is currently forming about 35 kilometers off the southeast coast of Hawaii. Loihi has already risen from the ocean floor to within 1 km of the surface, a distance of around 3 km. The hotspot theory predicts that if Loihi keeps expanding, it will eventually become the next island in the Hawaiian chain.

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The ________ committed themselves to achieving socialism without resorting to violent revolution and dictatorship.

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The Social Democrats committed themselves to achieving socialism without resorting to violent revolution and dictatorship. (Option B)

What is Socialism?

Socialism is a left-wing to far-left economic ideology and movement that encompasses a variety of economic systems typified by the supremacy of social ownership over private ownership of the means of production.

What is an excellent example of socialism?

Zambia's healthcare system is universal, making it a model of socialism.

Turkmenistan is a shining example of socialism, with government-subsidized electricity, many housing subsidies, and a primarily state-run economy.

Thus, it is right to state that the Social Democrats committed themselves to achieving socialism without resorting to violent revolution and dictatorship.

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Full Question:

The _____ committed themselves to achieving socialism without resorting to violent revolution and dictatorship.

a) communists

b) social democrats

c) Maoists

d) anarchists

In the united states, only ________ percent of infants are cared for exclusively by their mothers.

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In the united states, only 20 percent of infants are cared for exclusively by their mothers.

What is an exclusive care?

It refers to the social welfare service that is concerning the  support for nursery facilities, home fostering, taking care of and nurturing an infants in a healthy and safe manner while also providing them with education that is suitable for their mental and physical developmental characteristics.

In United states, about 20% of infants and toddlers are cared for exclusively by a parent and 29.5% percent of infants and toddlers attend home-based child care as their primary arrangement.

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Respecting the right of a patient with terminal cancer to refuse chemotherapy is based on a belief that the patient has the right to determine their own actions. what is this ethical principle?

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Respecting the right of a patient with terminal cancer to refuse chemotherapy is based on a belief that the patient has the right to determine their own actions. Autonomy is this ethical principle.

The idea that a terminally ill patient has the right to choose whether or not to receive chemotherapy is the foundation for respecting that patient's decision. This ethical premise is autonomy. Chemotherapy, often known as CTX or CTx, is a type of cancer treatment that involves administering one or more anti-cancer medications (also known as chemotherapeutic agents) as a prescribed course of treatment.

Chemotherapy may be administered with the intention of curing (which usually always requires drug combinations), extending life, or reducing symptoms (palliative chemotherapy). One of the main subspecialties of the medical field known as medical oncology, which is dedicated exclusively to pharmacotherapy for cancer, is chemotherapy.

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Janet receives disapproving looks from strangers for singing loudly while walking down the street. the disapproving looks janet receives are examples of:________

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Janet receives disapproving looks from strangers for singing loudly while walking down the street. The disapproving looks Janet receives are examples of informal sanctions.

What is informal sanctions?

Informal sanctions are actions in response to someone's behaviour that may serve to Informal punishments are responses to behavior that may help to deter nonconformity or promote adherence to a standard, guideline, or regulation. As a result, a sanction can be either positive or negative, encouraging or discouraging behavior that adheres to accepted notions of what is right or proper.

Peer punishments or displays of disapproval, like being'shushed' in a library, are examples of informal sanctions. The punishments meted out by organizations like the police are known as formal sanctions. We experience this when we breach the law. Simple instances are shaking one's head or giving someone a disapproving glance. Social isolation and remarks meant to incite embarrassment or shame, such as scorn or sarcasm, are examples of more overt informal sanctions.

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True or false: this result stems from both incumbent managers and outside bidders having perfect information.

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The given statement exists false. This result stems from both incumbent managers and outside bidders having perfect information.

Who are incumbent managers?The incumbent managers are appointed for a set period of time. When making a bid for holding office, outside bidders express their profit margins. Their performance will be inadequate if they are chosen for managerial positions.In order to get the job, an outsider tends to overbid, whereas an insider manager bids a realistic and achievable performance. An insider manager recognizes and attempts to control the factors that influence an organization's performance.Instead, incumbent managers typically have more experience and knowledge of offices and operations, making them more likely to perform well. As a result, despite their lower qualifications, these managers can perform admirably.

Therefore, the given statement is false.

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If there are 4 8-oz cups in a quart, about how many cups are in a 2-liter bottle of soda?

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If there are 4 8-oz cups in a quart, about, therefore 8 cups in a 2-liter bottle of soda are 8.

A quart is an English unit of extent same as a quarter gallon. three varieties of quarts are presently used: the liquid quart and dry quart of American commonplace devices and the imperial quart of the British imperial gadget. All are kind of equal to at least one liter. it's far divided into pints or 4 cups.

A liter is a unit of volume same as 1,000 cubic centimeters. The liter is a special call described for the cubic decimeter and is precisely equal to the volume of 1 cubic decimeter. The liter is an SI well-known unit for the extent to be used with the metric gadget.

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Ten-year-old kyle is sociable, athletic, and humorous, but he is also aggressive and disruptive. His peers view him as conceited. he would most likely be categorized as?

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Ten-year-old Kyle is sociable, athletic, and humorous, but he is also aggressive and disruptive. His peers view him as conceited. He would MOST likely be categorized as controversial.

What is a controversial person?

The term "controversial" refers to something or someone who is the focus of strong public debate, disagreement, or condemnation.

A person or item is considered controversial if it makes people angry or debate. The adjective form of the noun controversy is controversial, which is defined as a protracted argument, debate, or state of contention, particularly one that takes place in public and involves a significant difference of opinion.

When students disagree vehemently regarding words, assertions, or actions; when the topic touches on a specific sensitivity (such as political or religious); or when they experience an emotional response, topics frequently turn contentious.

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Which term refers to an area exposed to air or touch such as a vial, needle, or ampule?

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Compounding aseptic isolator refers to an area exposed to air or touch such as a vial, needle, or ampule.

What is isolator?

As indicated by the power framework area, the isolator can be characterized into three sorts of in particular transport side, line side and move transport side isolator. Transport Side Isolator is a kind of Isolator that interfaces by the significant transport. Electrical isolator or disconnector is a kind of mechanical switch that is utilized in electric circuits and gadgets with the primary capability of really confining two unique pieces of an instrument or power circuit. Sub-voltage type disconnection changes are utilized in the substation to permit the division of gear like transformers and circuit breakers. The isolator can be worked naturally or physically.

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Specialized and powerful programs, called ________, are typically used to create specialized commercial sites.

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Specialized and powerful programs, called Web authoring programs are typically used to create specialized commercial sites.

   Using current web writing tools and technologies, web authoring is the practice of producing online-based publications. Online authoring software is a form of desktop publishing tool that provides a distinct kind of graphical user interface to help users understand the challenging world of HTML and web coding.

     The end user can view a visual output that closely resembles the completed product using web authoring tools before the project is constructed. In that they often let users switch between an HTML code view and a visual design, web authoring tools are comparable to HTML editors in this regard. Because they enable the user to see something that resembles the finished project as they construct it, some of these tools are also known as WYSIWYG ("what you see is what you get") editors. For less experienced designers, the alternative is to hand code a project, which may be unpleasant, perplexing, and intimidating.

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sb help me Which statement describes the rate water passes or flows through a material?

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Answer:

your questions is wrong is make sure the spellings are correct

When an individual communicates from their critical parent ego state to another's child ego state, what kind of transaction are they said to be engaged in?

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An administrative worker who does not generally receive overtime pay is likely paid a: salary

What is overtime pay?

This a term used in business environment to mean payment coming as a result of working beyond the supposed closing time of work. An overtime pay is usually a percentage of the main pay which is usually called salary.

Overtime pay usually come inform of compensation to the worker hen we can conclude that an administrative worker who does not generally receive overtime pay is likely paid a: salary

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The ________ is the visible, bumpy portion of the ear. it is useful for helping to locate sounds.

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The Pinna is the visible, bumpy portion of the ear it is useful for helping to locate sounds. The pinna and outside ear channel create from the ectoderm of the primary branchial split.

What is Pinna?

The pinna is the main apparent piece of the ear (the auricle) with its extraordinary helical shape.

It is the initial segment of the external ear's life systems that responds to sound. The pinna's capability is to go about as a sort of channel which helps with coordinating the sound further into the ear.

The clinical term for the external ear is the auricle or pinna. The external ear is comprised of ligament and skin. The endoderm of the main pharyngeal pocket comes into contact with the ectoderm of the principal branchial split on day 11 of incubation to shape the tympanic layer.

Therefore Reflected sound off the pinna joins with the immediate sound into the ear to make high recurrence brush sifting impacts.

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Maura created a new, blank presentation and added a title to the title slide. she wants to save it before she continues working on it. what happens when she clicks the save button?

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When she clicks the saves button , then the name of a File name has to entre and then finally Saves the File.

What is PPT ?

A presentation created with Microsoft software that allows users to integrate audio, visual, and audio/visual components is known as a PowerPoint slideshow (PPT). It is regarded as a multimedia technology that also serves as a tool for sharing and collaborating on content.

What is a PowerPoint presentation, and how can I utilize it?

Microsoft PowerPoint is a powerful tool for making slide shows. As a component of the business's Microsoft Office suite software, it is packaged with Word, Excel, and other office productivity tools.. Slides are used in the program to provide multimedia-rich information.

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why unequal access to basic services amounts to social injustice

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unequal access to basic services amounts to social injustice because certain essential services are a prerequisite for living a decent life. It is vital to have access to items like housing, food, water, transportation, power, and other necessities of life. When particular individuals or communities lack access to these fundamental services, the outcome is likely to be either extreme poverty or death.

There are more than enough resources in the globe today to support every human on the planet, thanks to its abundance. However, due to the effective cost and the loss of profit brought about by the amassing of wealth and resources along with the idea of doing things for profit, individuals will no longer have access to these essential services. With $20 billion, homelessness in the US could be eradicated. Forty billion dollars could end world hunger. addressing these

Police brutality, educational inequity, and employment discrimination are a few examples of social injustice. Minorities and marginalized socioeconomic groups, such as the poor and members of minority ethnic groups, are the ones most vulnerable to it. Social injustice can harm anyone, but some of its main causes include racism, economic disparity, and class prejudice. Social injustice is when members of one group receive preferential treatment over members of another group due to that group's wealth, influence, or authority.

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why did the us make the national government weaker than the state governments under the articles of confederation

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The national government weaker than the state governments under the articles of confederation because a fragile central government was established under the Articles of Confederation.

The central government lacked sufficient power, and the Articles of Confederation lacked an executive or judicial branch. Congress was unable to control commerce. There was no population-based distribution of power in a representative government.

The Articles of Confederation's drafters deliberately crafted a weak central government. They desired to safeguard citizens' rights. They wished to limit the power of the government.

The Articles established a loose confederation of independent states with a meager central administration that delegated most authority to the state legislatures. Soon after, it was clear that the Federal government needed to be strengthened, which eventually prompted the Constitutional Convention in 1787.

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The term ______ is used to stress that the political, economic, and legal systems of a country are connected.

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The term Political Economy is used to stress that the political, economic, and legal systems of a country are connected.

This is further explained below.

What is Political Economy?

Generally, The field of political economics is an interdisciplinary subfield of the social sciences that focuses on the interconnections that exist between private citizens, public institutions, and governmental agendas.

Political economists investigate questions of how economic systems, such as capitalism, socialism, and communism, are implemented in actual economies.

Any economic theory, at its most fundamental level, is a system that is accepted as a means of managing the allocation of a limited quantity of resources in a manner that is advantageous for the largest number of persons.

In conclusion, The interconnected nature of a nation's political, economic, and legal institutions is referred to as the "political economy," and the phrase "political economy" is often used.

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An attribute that must have a value for every entity (or relationship) instance is a(n):____.

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An attribute that must have a value for every entity (or relationship) instance is a(n): required attribute

A boolean attribute is the Required attribute.

When present, it indicates that a field has to be completed before the form can be submitted.

The following input types are compatible with the required attribute: text, search, url, tel, email, password, date pickers, number, checkbox, radio, and file.

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The descriptive text that accompanies the packet analysis is provided by wireshark. true or false?

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The statement "The descriptive text that accompanies the packet analysis is provided by Wireshark. " is True

This is further explained below.

What is packet analysis?

Generally, The purpose of packet analysis, which is also known as packet sniffing or protocol analysis, is to comprehend what is occurring in a network by intercepting and capturing live data as it travels across the network. This is done using the term "packet analysis."

In conclusion,  It is correct to say that Wireshark is the one responsible for providing the descriptive text that is shown with the packet analysis.

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True or false: auditors should resist using analytical procedures during the substantive testing of balances.

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The statement is False, which means during the in-depth examination of balances or the substantive testing, the auditors should refrain from utilizing analytical techniques

How does substantive testing work?

A technique used by auditors called substantive testing examines a company’s financial statements, balances, accounts, and supporting documents for any errors or serious misstatements.

Substantive testing validates a company’s assertion that its financial records are true, correct, and valid by providing proof that no errors exist.

The auditor can establish a general opinion regarding the financial statements of the company using this conventional auditing technique.

According to the circumstance, an auditor may utilize a variety of different auditing techniques and tests, including substantive testing.

Examine board minutes from the board of directors to confirm that agreed dividends are actually paid. Contact suppliers to verify the accuracy of the account's payable amounts.

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Which cultural dimension reflects people's preference for relying on social norms?

Answers

uncertainty avoidance cultural dimension reflects people's preference for relying on social norms

This will be discussed in further detail below.

What exactly does it mean to avoid uncertainty?

In general, uncertainty avoidance is how different cultures vary in the degree of tolerance people have for unpredictability.

This concept comes up often in the field of cross-cultural psychology.

To sum everything up, Individuals' predisposition to rely on social standards is a reflection of the cultural factor known as uncertainty avoidance, which causes this predisposition.

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During cycle ergometer exercise, net efficiency decreases as the work rate increases. the mechanism to explain this observation is:________

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During cycle ergometer exercise, net efficiency decreases as the work rate increases. the mechanism to explain this observation is the connection between the amount of labor done and the amount of energy used is more of a curved than a linear one.

This is further explained below.

What is a cycle ergometer?

Generally, Ergometers are a specific kind of stationary bike called cycle ergometers.

They monitor the amount of energy that is expended and the quantity of exercise that is done when pedaling.

In conclusion, Increasing the work rate on a cycle ergometer leads to a drop in the overall efficiency of the workout.

This finding may be explained by the fact that the relationship between the amount of work done and the quantity of energy used is more of a curved than linear one.

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what was the colonial reaction to the quartering act?​

Answers

Protest in colonial legislatures. Bitter feelings between colonists and "redcoats". Led to "Boston Massacre" in March of 1770

In california, unless otherwise provided for, married couples will take title to real property as:_________

Answers

The correct answer is community property.

According to California Family Code section 760, community property is defined as "all property, real or personal, wherever situated, acquired by a married person during the marriage while domiciled in the state.". At the end of a divorce, community property is frequently divided equally.

In California, what does the phrase "community property" mean?

State community property laws apply in California. As a result, it is often assumed that both spouses own property, obtained by either partner throughout a marriage.

In California, how can a married couple hold title?

The most effective option for a married couple to take title is through a revocable trust. When you title property in your trust, you can keep the capital gains step up for the full asset on the first death and avoid probate upon the deaths of the first and surviving spouses.

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The airframe of a fixed wing aircraft is generally divided into 5 principla units, please list them:______.

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The airframe of a fixed wing aircraft is generally divided into 5 principal units. These are the fuselage, wings, stabilizers, flight control surfaces, and landing gear.

A fixed-wing aircraft is a heavier flying machines that flies by using its wings to generate life. The shape of its wings, and its speed, is what causes this lift motion. An example of a fixed-wing aircraft is an airplane.

An airplane has some essential components. This includes the fuselage, which is the main body of an aircraft that holds crews, passengers, and cargo. The wings are fin-like structures that produces lift. Flight control surfaces allow the pilot to control the airplane’s attitude, and landing gear is essential for safe landing.

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_________ psychology is the study and enhancement of positive feelings, traits, and abilities.

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Positive psychology is the scientific study of human strengths and virtues.

What is Positive psychology?

Positive psychology is a practical method for achieving peak performance and the scientific study of human flourishing. It has been described as the study of the qualities and strengths that help people, communities, and organizations flourish.

The study of the different factors that contribute to a happy and fulfilling life for both oneself and others is known as positive psychology (eg, positive emotions, life meaning, engaging work, and close relationships). It is the study of qualities and strengths.

Instead of focusing on fixing flaws, it encourages people to identify and develop their character strengths. In order to increase quality of life, positive psychology emphasizes the need for people to change their pessimistic perspective to one that is more upbeat.

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Mira is uninvolved in the lives of her children. she does not seem to know or care what they are doing. her parenting style might be best described as?

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Her parenting style might be best described as Diana Baumrind's styles of parenting .

Define Diana Baumrind's styles of parenting .

The terms authoritative, authoritarian, and permissive/indulgent were first used by clinical and developmental psychologist Diana Baumrind.

According to Diana Baumrind's "Pillar Theory," when kids get older and interact with more people, their behavior is directly related to their parents' parenting methods. The growth of children has traditionally been seen to be significantly influenced by parenting practices.

How would you define parenting style?

The combination of a parent's attitudes and behaviors toward their children, as well as the emotional context in which they act, is referred to as their parenting style.

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Identify the listening barriers.
a. Thought speed.
b. Nonverbal distractions.
c. Faking attention.
d. Grandstanding.
e. Psychological barriers.

Answers

The correct option is (c).  Listening barriers are Faking attention and Psychological barriers.

A psychological barrier is a state of mind that may prevent a person from making the best choices. The ability of people to communicate with others in a rational frame of mind is also impacted by psychological impediments. Emotional barriers are another name for psychological obstacles.

Communication can be impacted by the speaker's and listener's psychological states, for instance: Someone who struggles with social anxiety and/or low self-esteem may be too preoccupied with their appearance when speaking with a superior.

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Psychological barriers is the listening barriers.

Psychological noise, or noise stemming from our mental states including moods and degree of arousal, can facilitate or impede listening. Any mood or kingdom of arousal, positive or negative, that is too a ways above or below our regular baseline creates a barrier to message reception and processing. A mental barrier is a person's country of mind which can restriction their ability to make the proper decisions. psychological barriers additionally affect the human capacity to talk with others with a logical nation of mind. psychological barriers are also called emotional limitations. psychological barriers are due to the emotional character and mental limitations of people. those limitations result in absent-mindedness, the worry of expressing one's thoughts to others, excitement and emotional instability—all accounting for an overwhelming range of communication issues.

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Why did the western roman empire collapse in 476 ce, while the eastern roman (byzantine) empire continued to thrive?

Answers

The western roman empire collapsed in 476 ce, even as the Japanese roman (byzantine) empire persisted to thrive because, through the top of the fourth century CE, the Roman Empire become completely split into East and West. while the Byzantine Empire within the East thrived, the Western Roman Empire experienced a chain of invasions, a declining economy, and bad management.

The Roman Empire changed into the post-Republican duration of historic Rome. As a polity, it included massive territorial holdings across the Mediterranean Sea in Europe, North Africa, and Western Asia, ruled via emperors.

The Roman Empire turned into one of the finest and most influential civilizations in the world and lasted for over a thousand years. The quantity and period in their reign have made it tough to trace their rise to electricity and their fall. The Roman Empire turned into a based whilst Augustus Caesar proclaimed himself the first emperor of Rome in 31BC and came to an end with the fall of Constantinople in 1453CE. An empire is a political system in which a collection of human beings is dominated by a single person, an emperor or empress.

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The ____________ act(s) reiterated that the british had complete control over the colonies.

Answers

The declaratory act(s) reiterated that the British had complete control over the colonies.

What was the declaratory  act?

This was the declaration that the British government made tp the colonies in the year 1766. This was the act that was followed by the stamp act. The act was used as a way of trying to show the power that they had over the Americans in the colonies at the time before the declaration of independence was made.

Hence we can say that the declaratory act(s) reiterated that the British had complete control over the colonies.

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How many working days does a replacing insurer have to inform an existing insurer of replacement of life insurance? Exercise 2 Write the plural form of each noun. leaf Please help! This is a speaking test but I hope you can just type it out and I just read it.French version1. Parle des tes plans pour la premire (ou prochaine) fois que tu cherches un travail2. Organise les actions pour les prsenter en ordre.3. Utilise un minimum se cinq phrases compltes4. Assure-toi d'utiliser des expressions qui refltrent que tu vas faire ces actions dans le futur.English version:1. Talk about what you pan to do when you apply for your first (or next) job.2. Organize the process step by step and present it in order.3. Use a minimum of five complete sentences.4. Make sure to use expressions that reflect that you will be performing these actions in the future.Please answer it in French. This is for my Speaking test. Very important test. TIA! How were people governed before the Enlightenment? In practice, most companies list accounts on their trial balance in alphabetical order. True or false?. In a kinship system with matrilineal descent, who does a man inherit his rights to land and clan wealth from? What is the graetest comon factor on 18 12 How can you calculate the total capacitance of a series combination of capacitors?. PLEASE HELP, URGENT, POINTS GIVEN A sheet of paper contains a list of 5 double-digit prime numbers. Their mean is 31, while their median and mode is 29. The largest number is 41. Show how you can discover the 5 prime numbers written on the sheet. What is3 + 25 [2(2 - 3)(5 - 4) - 201] Which sentence is punctuated correctly?O "According to the U.S. Constitution." She said, "we all have the right to speak our minds."O "According to the U.S. Constitution" She said. "we all have the right to speak our minds."O "According to the U.S. Constitution," she said, "we all have the right to speak our minds."O "According to the U.S. Constitution," she said. "We all have the right to speak our minds."4 Simplifiy the expression 1/2 cubed - 6 divide 64 When two protons are extremely close to each other there is a strong __________ between them. Suppose a member of your family has become increasingly depressed in recent months, and its apparent that the person needs treatment. Youre chosen to look into the options and to make decisions about the treatment. Which layer of the atmosphere holds the ozone layer?Answer here__________ The difference between the variable costing ending inventory and the absorption costing ending inventory is:_________ If a firm has $300,000 in cash flow from assets and $100,000 in cash flow to shareholders, what is the cash flow to creditors? below is a list of volume of lava rates from four volcanoes. Which of the following is true of the rates at which lava flows? Choose all that apply. Fill in the blank set of stamps below with the value that would make the sets equal. An annuity is a stream of level, evenly spaced cash flows or cash payments that never ends. group of answer choices A. true B. false