Biology College

Carbapenems are b lactam antibiotics, as are penicillins and cephalosporins, which work by inhibiting cell wall biosynthesis in bacteria. In recent years, more cases, mostly in patients who have been hospitalized for a long period of time, of bacteria showing resistance to Carbapenems have been reported. In these patients, this drug could no long control bacterial infections. Check ALL the statements that are correct:



Question 1 options: Bacteria that are resistant to Carbapenems did not exist before these drugs were used.
Carbapenems are the selecting agent Bacteria become resistant only after they come into contact with Carbapenems
This development of drug resistance by bacteria is an example of evolution
Non-resistant bacteria become resistant strains via mutation
The rate of mutation (to resistant strains) is always increased by the use of Carbapenems
The rate of survival among resistant bacteria is always increased by the use of Carbapenems
The change from non-resistant to resistant bacterial strains are not due to changes in genes.
Cabapenem-resistant bacteria may come into existence if Carbapenems are not used.

Answers

Answer 1

Only once bacteria come into touch with carbapenems do they develop resistance. This bacterial drug resistance is an illustration of how non-resistant bacteria can mutate into resistant strains.

The original "carbapenem," thienamycin, would become the parent or model compound for all subsequent carbapenems. Recent research demonstrates unequivocally that carbapenem resistance is growing globally. In particular when porin losses occur, excessive synthesis of weak carbapenemases as CMY-10 and PDC Beta-lactamases might result in carbapenem resistance. Gram-positive bacteria develop resistance to carbapenems and other beta-lactam antibiotics through mutation-derived modifications to their PBPs, whereas Gram-negative bacteria frequently enlist the help of additional defense mechanisms to combat the effects of these drugs.

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Related Questions

You have the freedoms of ____ speech, press; and the right to ___ peacefully and petition the government

Answers

You have the freedoms of religion, speech, press; and the right to assemble peacefully and petition the government.

What is constitution of freedom?

Constitution of freedom governs certain laws that help its citizens to have freedom to choose what they like without any condition.

Indian constitution governs its citizens the freedom to choose any religion, follow it or practice it. There is freedom of speech and expression. They can peacefully assemble at any place and can move to any part of the country.

The citizens also have the right to practice any profession and have the freedom to report the government for law and justice.

Thus, constitution of freedom protects the fundamental rights of their citizens.

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